Greg,
Unconventional, but yes, Mr. Yates and others have said the beauty of waiting on a par 3 first hole is that, technically, those 10 minutes aren't included in the "4 hour, 15 minute" (or whatever) round. He says a course with 18 par 4 holes would play the fastest.
Other than that, balancing difficulty rather than a mix of harder and easier holes also helps flow, which also goes against the gca mantra of rhythm and flow. Turns out, you can have one or the other. For flow, having equally difficult holes, perhaps varied by difficult driving, approach shots and putting, with the other 2 challenges being somewhat easier, rather than a drop dead short, easy hole, helps flow, because the easy hole plays quick, and puts them on the next tee too soon.
Lastly, from a pure flow issue, having the hardest hole first, and then having each one just a bit easier would tend to let groups get out ahead and stay there, again, almost the reverse of the gentle handshake idea.
Times change, eh?