I gotta go along with Matt, and can't see how any golfer could honestly give up the best round of their LIFE, even if it is on an average course (not a Doak 0 course, just an average course, which many of us often play)
If this was measured against a once in a lifetime chance to play somewhere I really wanted to play I'd answer differently, but that's not what it says. It is just another round on a great classic course, which is always enjoyable but not worth giving up the best round of my life.
I think peer pressure is making people answer the way they think they should answer considering the audience, rather than being honest with themselves. Heck, I'm probably less concerned about the actual score I shoot than about anybody here -- Patrick Mucci once accused me of not even being a real golfer when I explained my approach to the game and what I found enjoyable about the game and the challenge of particular shots being ranked well above the 18 hole total I ended up with. But despite my relative lack of concern for my score I'd still love to have that one day where everything comes together and I shoot that career round I'll remember the rest of my life.