To analyze a bit further, your target spot is actually in the left half of the fairway (at 250 off the tee). The fairway is over 60 yards wide at that point. I don't know how wide your specific dispersion pattern is, but aiming a bit further left (say at the front left corner of the green) isn't going to hurt you much, its a minute adjustment.
It really takes a bad pull to get into serious trouble here. It happens a fair amount of the time because people get greedy, try to get to the green even when they can't (or for the weaker players worry too much about the carry), and end up pulling through the ball too much.
If you manage to find the left half, where your approach is aligned with the green, you really have three misses to most pins - a little short, left and a little long. From the right side, you only have long and left. Anything short or right on that line is going to leave you one of the toughest pitch shots on the property. [As an aside, for a front pin, I don't mind the right side, as the angle isn't as bad and the contours work for holding the shot.]
With respect to your lowest level of acceptable risk concept mentioned earlier, bearing in mind that we're playing golf and not flying a plane, I'd take the slight adjustment to the left on my target line with the hope of increasing my odds on the second shot. In the grand scheme of trying to make par here, which is my goal every time I play the hole, I know I'm much more likely to make a bogey or worse from a tee ball right of center. On this hole, on the tee, I'd be analyzing and balancing the risks associated with both the drive and the approach. To me, a slight risk on the drive outweighs a greater risk if I'm out of position on the 2nd shot.
Now contrast this with 6 at Pacific, another short par 4, this one even wider at about 90 yards in your 250 landing zone. If you played dead center of the fairway, left of the right side fairway bunker, you're going to be left with a pretty tough angle, sideways on a narrow green, with a quartering wind angle (or dead downwind in the winter to a narrow landing area). In order to get to a position that is aligned with the angle of the green, you have to play over that bunker, bringing the right side bunkers by the green into play, and even possibly the tree line right of the fairway. Is the risk worth it?
Doak takes a different approach here. He takes less club and tries to play as close to the fairway bunker as possible to avoid the contours further up in the middle that feed a ball left. He is going to take the risk of being near the bunker because he's comfortable with an approach from 100 to 120, not on the absolute best angle, but a better one than if he advanced the ball further and it fed further left.
These are totally different risk calculations than you get at 11 at Augusta. 11 isn't the narrowest hole on the course, but the real premium is on finding the fairway (as Erik has clearly shown). Where 11 gets really tricky is not because of the water, it is due to the contours at the front right of the green that can deflect an approach either left perhaps onto the green or right of the green leaving a tough up and down. A difference of only a few yards on your approach can lead to drastically different results, and its part of the reason why pins on the right side of that green can be as tough as pins close to the water. Because of this, I don't think there's really a preferred side to the fairway, as wherever you are its going to take an almost equally good shot to procure a good result.
If anything, this snapshot of three different holes just emphasizes how situational every shot can be. And yes, I understand that many of the variables that can come into play mean a player should be adjusting their target zone appropriately. But sometimes, just playing for a safe target zone with minimal risk is going to bring into play much greater risk on subsequent shots. It is the balancing of those risks that I'm trying to get at when I talk about playing out an entire hole while keeping angles in mind. Holes like 14 at Trails and 6 at Pac (along with a ton of other holes out here) ask you to make decisions on the tee, and its those kind of holes that make this game fun.
Sven
"Don't go left, don't go left. OK, you went left, try to get up and down from in front of the green."
Richard "Tour Rich" Perkins on the 6th at Pacific