#2 does it for me.
I've never played PV, but I've been very happy to have walked it 3 times. I remember walking up #1, and rounding to get to #2 tee. My thought when seeing #2 from the tee for the first time was "WOW - This is what all the hubbub is about".
I had never seen another hole come close.
But then I got to #3 and #4, etc, and realized like others have said, that PV has 18 amazing holes. Heck, the green on #18 with its huge size, is certainly great enough to call out for its own merits.