Bradley,
I don't think that one can make a valid assessment on a few plays, too much is simply randomness.
But, with repeat play of 20 times or more, I think you can start to establish playing patterns.
There are certain holes that present an awkwardness to my eye which translates into disturbing my comfort zone.
I try to figure out, what the architect has done to create this uneasiness, and how can I go about combating it.
There are a few holes that come to mind that can be bothersome, resulting in higher scores.
# 8 at GCGC and # 4 at Shackamaxon come to mind.
In both cases, the angle of the tee is at odds with the general alignment of the hole, which in turn creates an internal conflict for me.
Other holes which present an uncomfortable feeling are holes that present playing corridors which conflict with your general ball flight.
# 11 at ANGC might be a good example.
One gets the feeling, on the tee, that a draw will produce horrific results, yet, the ability to fade at will, often leads to an overexageration, a slice, that leads to more trouble.
I'd like to know what it is about the architect's presentation that causes golfers to have trouble with certain holes.