I am no longer long enough to reach virtually any part fives in two. Depending on the course, however, I can hit it into a greenside bunker in two from time to time.
Whether or not I aim for the bunker is a calculation I have to make on those types of holes. About half of the time I will not care whatsoever if I am in the bunker and the other half I would lay up short of it on purpose.
The biggest factor usually is how far of a bunker shot does it leave me to the pin. If it is more than 25 to 35 yards, then I will often opt to lay up short of the bunker. But if it is a truly greenside bunker and the pin is less than 30 yards, I will just bang it at the hole and if it goes in the bunker it goes in and if it stays out it stays out.