I'm partial to TOC #16, Corner of the Dyke. The OB fence on the right is like a water hazard that runs the length of the hole....but worse, since the penalty is stroke-and-distance. And, yes, you can aim your tee shot left of the bunker in the center of the fairway to avoid the so-called "amateur play," but then you're aiming back at the OB on your approach shot.
Another #16, this one at Belvedere in Charlevoix, MI, also makes my list. A small, elevated and heavily undulating green is very difficult to hit and hold, even with a wedge. And, the recovery shots from 30 or so feet below the green are diabolical.