While courses in Myrtle Beach cannot compare to Bandon, Pebble, Whistling Straits, or even courses within driving distance such as those at Pinehurst and Kiawah, golf on the Grand Strand can be quite fun and somtimes challenging with variety and sheer quantity that should provide at least moderate enjoyment.
That said -
Skip the TPC course - it is an unintersting course that the Sr. Tour abandoned a few year's back and one that you should pass over.
Heed the advice of many here and check out the Strantz designs at Caledonia and True Blue (but try to ignore the ninth at Caledonia where it looks like Mr. Strantz drew up a 17 hole layout and had to stick one more in to make it 18).
The Cobb-designed Surf Club (mentioned previously here) is an excellent and challenging (over 6800 from the back) traditional layout that was built long before Myrtle Beach began to attract such renowned architects as John Daly (Wicked Stick) and Lanny Wadkins (aforementioned TPC).
Other notable courses include River's Edge, Heather Glen (a fun Byrd/Johnson design) and Tidewater.
I'll be down in that area next week for Thanksgiving and already have rounds planned at the Surf Club. If you're going to be in the area, let me know and we'll put you down in a spot in our group.