Benjamin,
I think the open front allows lesser players to hit some area of the green with a run up, and if you really, really look at how the majority of golfers play, that is almost essential to their game. Also, forced carries just cause so many to choke, and rarely challenge the better players, so if we are designing a course to fit all, cross bunkering just seems like it should be a lightly used feature. Again, with the ball on a tee, and distance adjusted by multiple tees, a par 3 seems the best way to go if using this type of green once. Any short approach is probably acceptable.
As to the uphill, I would guess that many approaches would actually be on the third shot.
As to visibility, I just happen to like it, although you will see some on this board pushing for more blind holes, because visibility has become "too standard." Visibility makes golfers more comfortable, and I am not trying to put ants in anyone's pants during golf just to make them uncomfortable. (I guess they could sell canned ants in the pro shop if that's what golfers really want!) The thing I think compensates for a blind green's "unfairness" (another unfavorable buzzword around here, see the other thread) is the side front bunkers giving the golfer at least some idea of how wide the target is in absence of being able to see it, all of which helps plan the shot a little. Like you say, its probably futile, since they under club even on level ground, and usually fail to account for either wind or elevation change.
Of course, sometimes my emphasis on the viz can create a little tough situation in itself. If I tip the green up more than usual, add the false front, dipping down to the golfer, and have a steep fairway approach, it is quite possible to putt right off the green and end up 30-40 yards down the fairway, which no one likes, unless it happens to their opponent, of course.
I guess it can happen on a green with front hazard, too. A former employee, on the famous 16th at Dornick Hills in OK, played a driver off the deck to reach the fringe of this elevated green, famous for its rock cliff in front. He then shanked his chip back down to the fairway 50 feet below, and had to trudge back down to hit his third. He is a pretty good player, and it had to be the worst shot he ever hit.