JB,
Welcome to the discussions.
First, it seems as if the second is an up and over type hole. While good players might negotiate it ok, have you considered the rest of the players and whether they will be able to experience the second shot thrills, or whether they will be shooting blind to open sky over that hill? I can't tell from your description. Second, in any event, I have always felt that the key to good routing is to put it away for a week or two, and come back to it, rather than getting stuck on one idea. Time away always clarifies things for me, and I can't count the times when something that seemed like a must have on go around number 1 seemed trivial later on.
Architects use topo maps to draws cross sections along the centerline to get an idea of vision. With topo in hand, you should try the same on any hole you route, just to check.
To answer your questions -
TD is right on with the cross slopes, 10% or less on scruffy fw (like bluegrass) and maybe half that for consistent stretches on bent or other tighter fairways. Being uphill in the landing zone gives more leeway, as the uphill slope tends to kill the roll. Downhill and cross slope of 10% means most balls pull and Elvis, and leave the building....or fairway.
For most players, the tee shot tops out at 90-100 feet. For the 0.0001% of golfers who hit it like a tour pro, that can be as high as 130 feet. The flight is a parabola and the high point occurs about 2/3 of the total flight distance, or at about 200 for a 300 yard carry, 181 for 275, etc. There are online flight pattern calculators which are fun to play with. Grandma Gertie might get the ball half as high, or less.
As to the max uphill, there are two considerations - one if you want to see the green from the LZ, then it should be a maximum of 2% uphill, because that is about how much the green will usually tip from front to back. If vision isn't desired or possible, the 10% rule should apply. I'm not sure of exact figures, but you also need to consider whether the fairway mowers can pull up and down those long hills. A cross section will help determine what golfers would see on the tee shot, too. Seeing uphill slopes from the tee usually isn't a factor, but sometimes you would be surprised to know just what golfers won't see on that steeply downhill second shot over the ravine. Like Pebble Beach 8, and so many other places, it often turns out that the spectacular view can ONLY be seen from the very edge of the cliff.
Lastly, as on most steep sites, you need to consider what earthmoving can do to correct a situation that has some good features, but the details don't work. I know the mantra here is to move no earth, but I'm not familiar with too many mountain courses that don't level off hills and fill some valleys (enviro regulations permitting) to get a golf hole to playable condition.