I tend to agree with David, and would add the squads -- in terms of their style of play -- look remarkably similar. Kuchar, Dufner, Z. Johnson, Simpson and even Stricker and Snedeker are not guys I'd characterize as really long off the tee. And Euro has some really big hitters, with Rory, McDowell and Kaymer among them.
To me, RCups always come down to whether a few key competitors do better than expected. I think Rory and McDowell, who may play 4 times together, will be a bear for any US side to handle. Tiger simply has to play better than his past RCups, but he likes Medinah and has played well here, so I'm guessing he will -- he'll almost certainly play 5 times. And I'd expect Love to play short-hitters like Z. Johnson and Kuchar quite a bit (more than 3 times probably) because of their experience, and Snedeker a lot because he's the hottest guy on the US side.
On the US side, I'd look at how Snedeker, Simpson and Bubba play -- if those three have good RCups this week, the US should be in really good shape. For Euro, Kaymer, Poulter (who was great at Valhalla in a losing effort) and -- especially -- Sergio are the key guys.