Oahu Country Club, routed through a valley between two mountain ranges in 1913, features an overall elevation change of 410 Feet from the 4th Green (280 Feet) to the 15th Tee (690 Feet). The change is gradual so the course is fairly walkable. It takes 11 holes of meandering through the valley to get from the lowest point to the highest, but then the golfer benefits from the walk downhill (and prevailing wind) in their return to the clubhouse.
The architect incorporated the prevailing winds and the elevation change into their plans, as many of the shorter holes play uphill and into the wind, with longer holes playing downhill and with the wind. I felt it was a creative use of the elements to make a 6,000 yard course feel longer.
George Thomas actually has several photos of the course in his book, but unfortunately does not provide commentary (at least in the version that I have).