It depends what you want:
Fancy/resort style: Kiawah (ok golf to me wteo Ocean and 2 private courses), hilton head areas selection, or Palmetto bluff (1 course only)
Old/relaxed: Palmetto, Aiken Golf club, Midland Valley, or Sage Valley (not old or relaxed from what I hear)
Broad selection/public: Grand Strand (Dunes, Strantz courses, Barefoot selection, etc)
Close to Cola: Camden, Columbia CC, and one other course (Spring Valley or Forest Lake)