Paul Richards - I guess it would depend on two factors: what makes a course "worthy," and why you are seeking to play the courses. Do you want to play these courses simply for fun, or to expand your personal breadth of course knowledge, or to rate them for some panel?
There are a number of interesting courses from Greenville to Aiken, the best of which is Musgrove Mill. You casually mentioned several very private clubs, Sage Valley being the most private, so I assume access at any course must not be a problem for you. Is that the case?