At Kingston Heath, we have been playing the course in a different order on Wednesdays for almost 2 years now. This was to create two 9's which meant we could accommodate more players in the men's midweek comp, and still run a ladies comp in the morning. Operationally, it has worked really well, it has freed up the timesheet and quickened the pace of play. In the normal sequencing our 6th hole comes back to the clubhouse - so it makes it hard to have 2-tee starts.
Having played the course the 'right' way for 20 years, I am still struggling to come to terms with the Wednesday sequencing, because as Tom.D. said, the course has a very distinct 'flow' to it which I love. Obviously the holes are the same, but to me it is a different course with a different feel.
Someone playing the course for the first time on the 'Wednesday course' (which Ed.G will be doing in a months time
) would probably not think anything of it, but I will be certainly pointing out the usual sequencing and why I believe it works a lot better.