I think you'd probably see less emphasis on designing spectacular/tough/"signature" (etc.) finishing holes than we do at present, given that holes 18-17-16 wouldn't feature in a great many matches. You'd probably see more time and effort devoted to holes 12-13-14-15.
(By the way, not to hijack the thread, but I've often wondered what professional golf would be like with an inverted ratio of strokeplay to matchplay events - i.e. you'd have a couple of novelty strokeplay events, but the majority of competition was conducted at matchplay. Would it be almost exactly like the tennis circuit, or might variances emerge?)
Cheers,
Darren