On a par-3 I dont like to tee my ball up unless its 240ish or something and I have to use driver. Then the tee box, and how well it is manicured, becomes an issue. I think the tee boxes, at least on par-3's, should be mowed or cut down like fairway, to give the option of not teeing it up.
It should matter where a tee box is aimed. The only thing it does is play with you mentally, and true that can be tough, but also true is can easily be overcome. Its just a matter of aiming there.
On the other hand, if you are going to tee the ball up, then I guess the condition wouldnt really matter.